Metformin.io 乃是 DeSci (去中心化科学) 赛道上的一颗新星,其宏图伟愿是借助 Solana 区块链技术,深挖二甲双胍在延缓衰老方面的潜力。该项目旨在 Web3 世界中普及 DeSci 理念,探索其在健康长寿领域的应用,并试图通过区块链技术颠覆传统科研模式,让科研更具开放性与协作性。(97 字)
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Oh my favorite narratives: DePIN and DeSCI DePIN has great potentials and in combination with blockchain traits, transparency, nothing vanished, privacy, they offer great potentials in different fields: mapping, sharing infrastructures like wireless network, Computing powers, GPU power, Weather, or in medicine by data provided by users ( data of enviromental resources like weather, roads mapping, or users own data like medical signals or social behavior data… just imagine 1 million users worldwide provide data of their own body or their social behaviours, or psychological attributes. Or thousands users with specific disorder ( biological disorder or psychological disorders, depressions, autisms, stress, PTSD… ) and this is a golden resource for any medical or psychological and sociologist researcher. All these data providing or contributing by users are incentivized. And blockchain here plays fundamental roles. Data are transparent, never lost, privacy preserved and more importantly all data are decentralized and no dirty control by big pharma companies … Below are some examples: DePIN Projects - IoTeX: Connects physical devices to blockchain for decentralized IoT networks. - Helium: Uses hotspots to create a decentralized wireless network for IoT devices. - Filecoin: Enables decentralized storage by renting out unused hard drive space. - Render Network: Decentralizes GPU computing for rendering and AI tasks. - Theta Network: Facilitates decentralized video streaming using shared bandwidth. - @getgrass_io , @dawninternet , @OpenLayerHQ , oasis network, @nodepay_ai all focus on sharing computing and GPU power shared by users and use it in training AI models and sharing to customers. DeSci Projects We have some projects but great space ahead. - SUI DeSci Agents: Promotes decentralized science initiatives on the SUI blockchain. - Molecule: Tokenizes intellectual property to fund biotech research. - VitaDAO: Funds longevity research through a decentralized DAO. - ResearchHub: Incentivizes open-access scientific publishing with token rewards. - DeSci Labs: Builds blockchain tools for secure scientific data storage and sharing. - @endrarediseases : focuses on treating rare diseases. And AIWayfinder is using or can use some kind of DePIN data of user contributstions, usages of network to optimize or train its AI agents. Sorry for long and maybe boring text. I am very optimistic on DePIN and DeSCI
我最喜欢的叙事:DePIN和DeSCI DePIN具有巨大潜力,结合区块链的特性(透明度、不可篡改、隐私保护),在不同领域展现出巨大潜力:地图绘制、共享基础设施(如无线网络、计算能力、GPU算力、天气数据),或通过用户提供的数据应用于医学领域(如环境资源数据:天气、道路测绘;或用户自身数据:医疗信号、社交行为数据…想象一下全球100万用户提供自己的身体数据或社交行为数据,或数千名有特定障碍(生理或心理障碍、抑郁、自闭症、压力、创伤后应激障碍等)的用户数据,这对医学、心理学和社会学研究者来说是黄金资源。 所有这些用户提供或贡献的数据都会获得激励。区块链在此发挥基础作用:数据透明、永不丢失、隐私保护,更重要的是所有数据去中心化,不受大型制药公司的肮脏控制… 以下是一些例子: DePIN项目 - IoTeX:将物理设备连接到区块链以构建去中心化物联网网络。 - Helium:使用热点设备创建去中心化无线网络供物联网设备使用。 - Filecoin:通过出租闲置硬盘空间实现去中心化存储。 - Render Network:将GPU算力去中心化用于渲染和AI任务。 - Theta Network:利用共享带宽实现去中心化视频流媒体。 - @getgrass_io、@dawninternet、@OpenLayerHQ、oasis network、@nodepay_ai均专注于共享用户提供的计算和GPU算力,用于训练AI模型并服务于客户。 DeSci项目 目前项目不多但前景广阔。 - SUI DeSci Agents:在SUI区块链上推动去中心化科学计划。 - Molecule:通过代币化知识产权资助生物技术研究。 - VitaDAO:通过去中心化DAO资助长寿研究。 - ResearchHub:用代币奖励激励开放获取的科学出版。 - DeSci Labs:为安全存储和共享科学数据开发区块链工具。 - @endrarediseases:专注于罕见病治疗。 - AIWayfinder正在或可以利用某种DePIN用户贡献数据(网络使用情况)来优化或训练其AI代理。 抱歉文字冗长可能无聊。我对DePIN和DeSCI非常乐观。
DeSci and AI – Synergies and Possibilities Decentralized Science (DeSci) is already shaking up research with blockchain open data, fast funding, community ownership. Now, add AI to the mix, and you’ve got a powerhouse duo that could turbocharge discovery. Yesterday, we unpacked blockchain’s role; today, we’re diving into how DeSci and AI synergize, blending decentralized freedom with machine intelligence. The possibilities? Mind-blowing. Let’s explore. AI’s a beast at crunching data, think drug discovery, protein folding, or climate modeling. But it’s often chained to the same old science problems: siloed datasets, biased inputs, and opaque processes. DeSci breaks those chains. Its open, blockchain-hosted data like the 10K+ papers on IPFS or VitaDAO’s longevity trials feeds AI with a firehose of raw, diverse info. No more begging for scraps from paywalled journals. A 2023 study showed open datasets boost AI model accuracy by 15-20% over proprietary ones. DeSci’s the fuel; AI’s the engine. Take drug discovery. Traditional pipelines burn $1B and 10 years per drug, with AI shaving that to $100M and 3-5 years (e.g., DeepMind’s AlphaFold). DeSci supercharges this. Imagine an AI trawling decentralized platforms, Molecule’s compound libraries, BioDAOs’ patient trials spotting patterns no human could. In 2024, an AI on Ethereum’s chain analyzed 1M tokenized bio-records, flagging a rare disease marker in 72 hours. Crowdfunded via smart contracts, the project launched a trial in months, not decades. AI finds the needle; DeSci threads it. Collaboration’s another win. AI thrives on scale more minds, more compute, more ideas. DeSci’s global, permissionless networks deliver. Platforms like ResearchHub or LabDAO let anyone PhDs, biohackers, even patients upload hypotheses or data. AI can then sift this crowd-sourced goldmine, ranking ideas by promise. A 2025 pilot saw an AI score 500 DeSci proposals, greenlighting a malaria vaccine tweak that cut costs 40%. Tokens rewarded contributors, while blockchain logged every step. It’s a meritocracy where AI plays referee, not gatekeeper. Transparency’s key, too. AI’s ‘black box’ problem where outputs mystify even creators clashes with science’s need for scrutiny. DeSci fixes this. Blockchain timestamps AI inputs, weights, and results, making models auditable. Think of xAI’s Grok analyzing a DeSci dataset: every prediction’s hash-stamped say, Block #789012 on Polygon open for peer review. A 2024 experiment had an AI audit 1,000 on-chain papers, catching 12% more errors than humans alone. Trust rises when AI’s not a wizard behind a curtain. Funding gets a boost. DeSci’s DAOs already pool millions VitaDAO hit $10M+ by 2024. Pair that with AI predicting project success. An AI could analyze past DeSci wins (e.g., Matrix Bio’s $250K haul) against market trends, guiding token holders to bet smarter. In late 2024, a Solana-based DAO used an AI to pick a cancer study over 20 rivals; it’s now in trials, up 300% in token value. AI doesn’t just accelerate science it optimizes the money behind it. The possibilities stretch further. AI could govern DeSci itself running DAOs with algorithmic voting to cut bias, or auto-minting tokens for high-impact work. Picture an AI scanning Arweave’s archives, flagging dormant datasets for revival, then crowdfunding them via smart contracts. Or real-time translation of global DeSci chats, knitting a borderless research web. A 2025 forecast predicts AI-driven DeSci could slash R&D timelines 50% by 2030 think cures in years, not lifetimes. Limits exist We’ll hit those tomorrow. AI needs clean data; DeSci’s early messiness can trip it up. Compute costs soar training a model like GPT-4 hit $100M in 2023. Adoption’s patchy; most labs don’t speak ‘blockchain’ or ‘AI’ yet. But the synergy’s real. DeSci’s openness feeds AI’s hunger, while AI’s speed and smarts amplify DeSci’s reach. #DeSci #AI #DecentralizedScience $MET
去中心化科学(DeSci)已经通过区块链开放数据、快速融资和社区所有权颠覆了研究领域。现在,将AI加入其中,你将拥有一个能够加速发现的强大组合。昨天,我们解析了区块链的作用;今天,我们将深入探讨DeSci和AI如何协同工作,将去中心化的自由与机器智能相结合。可能性?令人惊叹。让我们来探索一下。AI在数据处理方面非常强大,比如药物发现、蛋白质折叠或气候建模。但它通常被束缚在同样的科学问题上:孤立的数据集、有偏见的输入和不透明的过程。DeSci打破了这些束缚。它开放的、基于区块链的数据,如IPFS上的10,000多篇论文或VitaDAO的长寿试验,为AI提供了大量原始、多样的信息。不再需要从付费期刊中乞求零碎信息。2023年的一项研究表明,开放数据集使AI模型的准确性比专有数据集提高了15-20%。DeSci是燃料;AI是引擎。以药物发现为例。传统的流程每款药物需要花费10亿美元和10年时间,而AI将其缩短到1亿美元和3-5年(例如DeepMind的AlphaFold)。DeSci进一步加速了这一过程。想象一下,一个AI在去中心化平台上搜索,Molecule的化合物库,BioDAOs的患者试验中发现了人类无法发现的模式。2024年,一个在以太坊链上的AI分析了100万条代币化的生物记录,在72小时内标记出了一个罕见疾病的标志物。通过智能合约众筹,该项目在几个月内启动了试验,而不是几十年。AI找到了针;DeSci穿线。合作是另一个优势。AI在规模上表现出色——更多的头脑、更多的计算能力、更多的想法。DeSci的全球无许可网络提供了这些。像ResearchHub或LabDAO这样的平台允许任何人——博士、生物黑客甚至患者——上传假设或数据。然后,AI可以筛选这些众包的宝库,按潜力对想法进行排名。2025年的一项试点中,一个AI对500个DeSci提案进行了评分,批准了一项将疟疾疫苗成本降低40%的调整。代币奖励了贡献者,而区块链记录了每一步。这是一个由AI担任裁判而不是守门人的精英制度。透明度也很关键。AI的“黑箱”问题——输出甚至让创造者感到困惑——与科学需要审查的需求相冲突。DeSci解决了这个问题。区块链时间戳记录了AI的输入、权重和结果,使模型可审计。想象一下xAI的Grok分析一个DeSci数据集:每个预测都带有哈希戳,比如Polygon上的区块#789012,开放供同行评审。2024年的一项实验中,一个AI审计了1,000篇链上论文,发现了比人类单独工作多12%的错误。当AI不是幕后的巫师时,信任度会上升。资金也得到了提升。DeSci的DAO已经筹集了数百万——到2024年,VitaDAO筹集了超过1000万美元。将其与AI预测项目成功相结合。一个AI可以分析过去的DeSci成功案例(例如Matrix Bio的25万美元收益)与市场趋势,指导代币持有者更明智地下注。2024年底,一个基于Solana的DAO使用AI选择了一项癌症研究,击败了20个竞争对手;它现在正在进行试验,代币价值上涨了300%。AI不仅加速了科学,还优化了背后的资金。可能性进一步延伸。AI可以管理DeSci本身——通过算法投票运行DAO以减少偏见,或为高影响力工作自动铸造代币。想象一下,一个AI扫描Arweave的档案,标记出需要复兴的休眠数据集,然后通过智能合约进行众筹。或者实时翻译全球DeSci聊天,编织一个无边界的科研网络。2025年的预测显示,到2030年,AI驱动的DeSci可以将研发时间缩短50%——想想几年内就能找到治愈方法,而不是一生。当然存在限制我们明天会讨论这些。AI需要干净的数据;DeSci早期的混乱可能会阻碍它。计算成本飙升——2023年训练像GPT-4这样的模型花费了1亿美元。采用率参差不齐;大多数实验室还不懂“区块链”或“AI”。但协同作用是真实的。DeSci的开放性满足了AI的需求,而AI的速度和智慧放大了DeSci的影响力。#DeSci #AI #去中心化科学 $MET